Session Chairs:
Christina Guzzo, University of Toronto
Roy Duncan, Dalhousie University 
 

Invited Speaker: Christina Guzzo
Session Title: Dusting for Fingerprints: Human Proteins on HIV-1 Virions as Clues to Virus–Host Interactions

Oral Abstracts:

• Gut microbiota regulates antiviral immunity in the vaginal mucosa during HSV-2 infection
  Nuzhat Rahman, McMaster University
• Asymmetric structural transitions in the icosahedral organization of EEEV.
  ABHISHEK BANDYOPADHYAY, Purdue University
• Newcastle disease virus vectored vaccines against Nipah virus confer protection against lethal challenge in Syrian hamsters and African green monkeys (AGM)
  Melanie Goens, University of Guelph

This session profiles the impactful research of two promising Early Career Researchers (ECRs) that have been supported through CIHR funding competitions. The session recognizes the excellence of health research being done in Canada by new investigators in the field of infection and immunity. The Speakers will highlight how their research has addressed critical gaps and provide insights on how researchers who are earlier in their careers can establish impactful research programs. Attendees will have the opportunity to actively engage the speakers in critical reflection on their work and career journeys.

10:15 – 10:30
CIHR-III Welcome & Overview (10 min) + Q&A (5 min)
Moderator: Dr. Jimmy Dikeakos, Professor (Western University), Chair of CIHR HIV/AIDS and Vice-Chair of STBBI Research Advisory Committee

10:30– 10 :50
ECR presentation (15 min + 5 min Q&A):
Speaker : Anil Kumar, Assistant Professor, Biochemistry, Microbiology & Immunology, University of Saskatchewan
Website: https://medicine.usask.ca/profiles/biochemistry-microbiologyimmunology/anil-kumar-v.-ansalem.php
Title: Human Microproteins in Virus Infection and Immunity

10:50 – 11:10
ECR presentation (15 min + 5 min Q&A)
Speaker: Julie Lajoie, Assistant Professor, University of Manitoba, Max Rady College of Medicine,Francis A. Plummer Professorship in Global Infectious Diseases;
Website: https://umanitoba.ca/medicine/faculty-staff/julie-lajoie
Title: Not Just Biology: DMPA, HIV Vulnerability, and Structural Inequities

11:10-11:15
Closing and Final Questions

• Nasal Commensal Bacteria Differentially Modulate Epithelial ACE2 and TMPRSS2 Expression and SARS-CoV-2 Permissiveness in a Primary Air-Liquid Interface Model
  Zeynep Gunes Tepe Demir, Western University
• Ebola virus trafficking factor PIKfyve-VAC14-FIG4 complex assembly is regulated by calmodulin binding
  Agnitha Xavier, University of Ottawa
• Susceptibility of Porcine Mammary Gland to Highly Pathogenic Avian Influenza (HPAI) virus Infection
  Ulises Barron Castillo, University of Saskatchewan
• Leveraging the HIV-1-incorporated human proteome to better understand virus-host interactions
  Arvin Persaud, University of Toronto Scarborough
• Characterization of inhibitors targeting the interaction between Nef and Src family kinases
  Maxine Nicolais, Western University

Session Chairs:
Yan Zhou, The Vaccine and Infectious Disease Organization
Laurent Chatel-Chaix, Institut national de la recherche scientifique

Invited Speaker:  Denys A. Khaperskyy
Session Title:  Viral cleanup crew: host shutoff nucleases and virus replication

Oral Abstracts:

• Decoding the distinct innate immune evasion abilities of human coronavirus nucleocapsid proteins|
  Noga Sharlin, University of Calgary
• Staphylococcus aureus enhances influenza A virus replication through manipulation of cellular vacuole sorting
  Veerle Appels, University of Victoria
• Construction of alphavirus replicons to explore differences in tissue tropism and pathogenesis
  Dan Boghici, McGill University
• Binding of the Birnavirus VP3 protein to the Early Endosomal Antigen 1 (EEA1) Drives Organellar Remodeling and Trafficking of Virus-hijacked Endosomes
  Maria Cecilia Gimenez, University of Toronto
• A mitoproteomic analysis of flavivirus-infected cells unveils the proviral role of PLA2G15 via the alteration of lysosomal and mitochondrial dynamics
  Viviana Andrea Barragan Torres, INRS - Institut Armand-Frappier
• Elucidating the molecular constituents of hepatitis C virus replication organelles
  Nathan Pilkey, The University of British Columbia
• KSHV requires eIF3d for cholesterol biosynthesis to support lytic replication
  Eric Pringle, Dalhousie

Session Chairs:
Leo Liu, McGill University
Che Colpitts, Queens University

Invited Speaker:  Sébastien Nisole
Session Title:  Discovering cellular antiviral factors targeting flaviviruses and other RNA viruses

Oral Abstracts:

• Impaired host shutoff is a fitness cost associated with baloxavir marboxil resistance mutations in influenza A virus PA/PA-X nuclease domain
  Jack Case, Dalhousie University
• Rewiring Host RNA Metabolism: A Multifunctional Viral Protein Alters mRNA Processing
  Iris Shen, Jan lab, University of British Columbia
• Organelle Immunoprecipitation Reveals Remodelling of the Mitochondrial Proteome During Herpes Simplex Virus Type 2 Infection
  Safara Holder, Queen's University

For those signed up for the Dine-Around experience at a selection of Guelph’s most popular restaurants, a shuttle will pick you up from the Delta Hotel and transport you to your assigned restaurant. Advance sign-up is required through the registration page.

The Trainee Networking Dinner will take place at the Delta Hotel with an opportunity for trainees to connect and expand their network. Advance sign-up was required. 

To view the table assignments click HERE. 

Session Chairs:
Leo Liu, McGill University
Che Colpitts, Queens University

Oral Abstracts:

• Autophagy-dependent secretion in influenza A virus infection
  Andrew Leidal, University of Calgary
• HCMV UL78 is Localized to the Nucleus and Required for Efficient Viral Reactivation from Latent Infection
  Meaghan Hancock, University of Guelph
• Developing a Trivalent Long Double-Stranded RNA Strategy Targeting Three Major Respiratory Viruses
  Shawn Carr, Wilfrid Laurier University
• ARGLU1 Limits Adenoviral Transcription and Modulates DNA Damage Response
  Amit Koul, Univeristy of Manitoba
• Uniform positioning of lysosomes by Arl8b impairs Ebola virus like particle entry.
  Redaet Daniel, University of Ottawa
• Human long non-coding RNA LINC00887 encoded microprotein suppresses Enterovirus D68 replication
  Nasim Akbari, University of Sasketchewan

Session Chairs:
Vivian Liu, McGill University
Bruce Banfield, Queens University 

Invited Speaker:  Maya Shmulevitz
Session Title: Core-ordinating replication versus full assembly of dsRNA viruses

Oral Abstracts:

• Disruption of lipid metabolism by thapsigargin inhibits multiple stages of the heptatits C virus life cycle
  Trinity Tooley-Macarandang, Queen's University
• Impact of SARS-CoV-2 accessory protein ORF8 on NK cell activation and function
  Katrina Dionne, Université de Montréal
• Coxsackievirus B3 Infection Reprograms Extracellular Vesicle Biogenesis and Cargo to Amplify Cardiac Inflammation in Viral Myocarditis
  Amirhossein Bahreyni, University of British Columbia
• A Membrane Embedded Trigger: PI(4,5)P₂ Initiates HPIV3 Matrix Self Assembly and Budding
  David Van Ommen, University of Toronto
• Human parainfluenza virus 3 inclusion bodies segregate RNA synthesis from protein translation and regulate virion assembly\
  Stephen Lee, University of Alberta

• KSHV kaposin is a bifunctional RNA that employs a dual mechanism to mediate processing body disassembly
  Maxwell Bui-Marinos, University of Calgary
• Transcriptomic profiling reveals early immune activation and metabolic remodeling in lymphoid tissues following in ovo Marek's disease virus mRNA vaccination in chickens
  Janan Shoja Doost, University of Guelph
• Investigating mRNA COVID-19 vaccine-induced trained innate immunity in older/frail populations
  Kyle Amaral, McMaster University
• Tankyrase inhibition enhances peroxisome-mediated antiviral responses and identifies broad-spectrum antiviral candidates
  Jumari Snyman, University of Alberta
• Investigating the Role of Ubiquitin-Like Modification of the Zika Virus Nonstructural Proteins in Virion Assembly
  Olivia Klann, University of British Columbia

Session Chairs: 
Guy Boivin, Université Laval
Barbara Porto, University of Manitoba 

Invited Speaker: Erwan Pernet
Session Title: Macrophages and inflammatory responses in the neonatal lungs

Oral Abstracts:

• Pre-clinical studies of BHV-1 virotherapy in a humanized mouse model of pancreatic ductal adenocarcinoma with HLA class I match
  Maria Davola, McMaster University
• RSV Infection is Impaired after B-Raf Kinase Blockade in Airway Epithelial Cells
  Júlia Cerato, University of Manitoba
• Differential neuroinflammatory, degenerative, and ultrastructural outcomes of SARS-CoV-2 infection in male and female MPTP-exposed K18-hACE2 mice
  Ifeoluwa Oluleke Awogbindin, University of Victoria, Victoria, Canada
• Deciphering the role of microglia in Zika virus-induced neuroinflammation and pathogenesis during fetal brain developmen
  Olus Uyar, INRS-Armand-Frappier Santé Biotechnologie Research Centre

Posters presented today should plan to be at their posters from 5:00pm - 6:00pm. 

Session Chairs:
John Law, Memorial University
Alyson Kelvin , University of Calgary

Invited Speaker: Barbara Porto
Session Title: Interferon lambda as a novel antiviral approach for respiratory syncytial virus infection

Oral Abstracts:

• An active machine learning approach to novel antiviral discovery against influenza
  Hahn Li, McMaster University
• Single-cell profiling reveals oncolytic vaccinia virus–driven reprogramming of the tumour immune microenvironment.
  Jun Li Wang, University of Alberta
• Nasal versus bronchial responses to rhinovirus infection in children with recurrent wheeze
  Cameron Griffiths, University of Virginia

Session Chairs:
John Law, Memorial University
Alyson Kelvin , University of Calgary

Oral Abstracts:

• Recombinant HMPV vector: a versatile integrated approach for immunization against respiratory viruses
  Elhadji Birane MBOUP, Université LAVAL
• Antibody-Dependent Cell Mediated Cytotoxicity (ADCC) to multiple subtypes of influenza virus is induced by a VSV-based universal influenza vaccine
  Maryann Wendy Akumu Buyu, University of Manitoba

• TRIM5α: Dual-edged sword in bats
  Sauhard Shrivastava, University of Saskatchewan (VIDO)
• Generation of a Mpox Clade 1b reporter viruses for high throughput drug screening
  Juveriya Qamar Khan, University of Saskatchewan
• Network-based detection of HIV-1 recombination reveals underlying subtype architecture
  Abayomi Olabode, Western university
• Prevalence of antibodies against California serogroup orthobunyaviruses in residents of Newfoundland and Labrador, Canada
  Jordan Wight, University of Manitoba
• Avian H3N9 Replication Dynamics and Age-Associated Pathogenicity in Young and Aged Male C57BL/6 Mice
  Rubee Bavananthasivam, National Research Council

Session Chairs: 
Michael J. Norris, University of Toronto
Ann Gregory, University of Calgary

Invited Speaker:  Ann Gregory
Session Title: Uncovering Hidden Viruses Across the Human Body.

Oral Abstracts:

• Testing for a wildlife reservoir of divergent SARS-CoV-2 in white-tailed deer
  Lauren Crawshaw, Ministry of Natural Resources
• Evolutionary insights and genomic analysis of betacoronaviruses in wild Peromyscus mice and other terrestrial small mammals
  Simon Jeeves, University of Guelph
• Host Finder: computational detection of virus-host interactions by large-scale data-mining of the Sequence Read Archive
  Shyan Mascarenhas, University of Waterloo
• Predicting H5Nx influenza virus host taxa using viral genomic features and phylogenetically cross-validated machine learning models
  Angela McLaughlin, Dalhousie University

Moderator: 
Samira Mubareka, University of Toronto

Panelists:
Andrea Gamarnik, Fundación Instituto Leloir
Bryce Warner, Vaccine And Infectious Disease Organization
Jason Kindrachuk, University of Manitoba 

The session will conclude with an interactive Q&A period for audience questions.

Session Chairs:
Samira Mubareka, Sunnybrook Research Institute 
Eric Arts, Western University

Invited Speaker:  Miguel E. Quiñones-Mateu
Session Title: Potential for SARS-CoV-2 Reverse Zoonosis in Domestic and Invasive Mammal Species in Aotearoa New Zealand

Oral Abstracts:

• ​​Phylogenetic analysis and ​phenotypic evaluation of zoonotic influenza A/H9N2 viruses in Cambodia
  Brown Bulloch, Université Laval
• Sewage reoviruses persist and shed for longer following in vivo oral infection compared lab-adapted strains.
  Qi Feng Lin, University of Alberta
• Ancestral Reconstruction Supports that Loss of Nef-mediated T Cell Modulation Coincided with the Emergence of Pathogenic Lentiviruses
  Angelina Baldino, Western University
• Interferon beta specificity in humans and bats contributes to differences in viral replication and tolerance
  Rita Maria Quintela Tizon, Vaccine and Infectious Disease Organization / University of Saskatchewan